Medication Cost & Access Resource
A practical guide to where patients may look for common weight-management medications
Rough estimates only. Prices vary by pharmacy, dose, insurance coverage, location, coupon eligibility, and availability. This patient is meant for general resource only and does not guarantee coverage or prescribing.
Best places to check first
Insurance Portal
Manufacturer savings pages
GoodRx
SingleCare
Amazon Pharmacy
Local Retail Pharmacy
Medication
Places to look
Estimated price
Tirzepatide
(Zepbound)
• zepbound.lilly.com
• LillyDirect / lillydirect.lilly.com
• GoodRx.com/zepbound
• SingleCare.com/prescription/zepbound
• Local retail pharmacy
• Self-pay direct options may be about $299–$699/month
• Retail/list pricing may range about $499–$1,000+ per fill
• Insurance coverage varies
Wegovy
(semaglutide injection)
• wegovy.com
• NovoCare / novocare.com
• GoodRx.com/wegovy
• SingleCare.com/prescription/wegovy
• Amazon Pharmacy or local retail pharmacy
• Retail/list pricing often about $1,200–$1,350/month
• Eligible savings programs may reduce cost
• Insurance coverage varies
Saxenda
(Liraglutide)
• saxenda.com
• NovoCare / novocare.com
• GoodRx.com/saxenda
• SingleCare.com/prescription/saxenda
• Local retail pharmacy
• Retail/list pricing often about $1,350–$1,600/month
• Eligible patients may have savings programs
• Insurance coverage varies
Contrave
(bupropion/naloxone ER)
• contrave.com/save
• CurAccess Program
• GoodRx.com/contrave
• SingleCare.com/prescription/contrave
• Amazon Pharmacy or local retail pharmacy
• CurAccess often about $99/month
• GoodRx cash pricing may be about $199/month
• Retail cash pricing may be higher depending on pharmacy
Orlistat/
Xenical/ Alli
• GoodRx.com/orlistat
• GoodRx.com/xenical
• SingleCare.com/prescription/orlistat
• Amazon for OTC Alli
• Local retail pharmacy
• Generic orlistat coupons may be about $40–$65
• Retail pricing may be about $600–$725
• OTC Alli is often about $40–$60+
Imcivree
(setmelanotide)
• imcivree.com
• Rhythm patient support resources
• Specialty pharmacy
• Insurance prior authorization pathway
• High-cost specialty medication
• Annual cost may exceed about $294,000–$441,000
• Coverage and eligibility are highly specific
Metformin
• GoodRx.com/metformin
• SingleCare.com/prescription/metformin
• Pharmacy.amazon.com
• Local retail pharmacy
• Common low-cost generic
• Often about $4–$25/month
• Some Amazon-preferred pricing may be around $1–$8
Topiramate
• GoodRx.com/topiramate
• SingleCare.com/prescription/topiramate
• Pharmacy.amazon.com
• Local retail pharmacy
• Immediate-release generic often about $4–$25/month
• Extended-release forms may cost more
Rybelsus
(oral semaglutide)
• rybelsus.com
• NovoCare / novocare.com
• GoodRx.com/rybelsus
• SingleCare.com/prescription/rybelsus
• Local or mail-order pharmacy
• Retail/list pricing often about $1,000–$1,100/month
• Eligible savings programs may reduce cost
• Coverage varies; weight-management use may be off-label
Important Notes
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This is a general resource only
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Manufacturer programs often apply only to eligible commercially insured patients and may exclude Medicare or Medicaid.
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Many GLP-1 medications require prior authorization and may have supply changes
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Cash, coupon, and insurance prices can all differ.
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Ask your pharmacy to compare insurance, cash, and coupon pricing